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portada Drug-excipient-shell interactions using thermoplastic capsules
Type
Physical Book
Language
English
Pages
192
Format
Paperback
Dimensions
22.9x15.2x1.1 cm
Weight
0.29 kg.
ISBN13
9786202007146
Categories

Drug-excipient-shell interactions using thermoplastic capsules

Zdravka Misic (Author) · Martin Kuentz (Author) · Georgios Imanidis (Author) · LAP Lambert Academic Publishing · Paperback

Drug-excipient-shell interactions using thermoplastic capsules - Misic, Zdravka ; Kuentz, Martin ; Imanidis, Georgios

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Synopsis "Drug-excipient-shell interactions using thermoplastic capsules"

This book introduced novel starch-based thermoplastic capsules (S-PVA-Cs) and demonstrated their advantage over SGCs with respect to hydrophilic lipid-based formulations. Release studies in biorelevant media revealed differences in how formulations hydrated and interacted with the shell material. Drug-excipient-shell interactions were observed in various capsule types (SGCs, S-PVA-Cs, and VegaGels(R)) at different levels of biopharmaceutical in vitro testing. A better mechanistic understanding was attained that may guide future development of soft capsule products.

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