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portada Hiv-1 Latency
Type
Physical Book
Publisher
Author
Language
English
Pages
248
Format
Paperback
Dimensions
23.4x15.6x1.4 cm
Weight
0.37 kg.
ISBN13
9783030132149
Categories

Hiv-1 Latency

Silvestri, Guido ; Lichterfeld, Mathias (Author) · Springer · Paperback

Hiv-1 Latency - Silvestri, Guido ; Lichterfeld, Mathias

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Synopsis "Hiv-1 Latency"

This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.

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