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portada Long Non-Coding RNAs - Function, Mechanisms, and Applications: Function, Mechanisms, and Applications
Type
Physical Book
Publisher
Author
Language
English
Pages
214
Format
Hardcover
Dimensions
25.4x17.8x1.3 cm
ISBN13
9781836344797

Long Non-Coding RNAs - Function, Mechanisms, and Applications: Function, Mechanisms, and Applications

Tutar, Yusuf; Ikehara, Kenji; Tutar, Lütfi (Author) · Intechopen · Hardcover

Long Non-Coding RNAs - Function, Mechanisms, and Applications: Function, Mechanisms, and Applications - Tutar, Yusuf; Ikehara, Kenji; Tutar, Lütfi

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Synopsis "Long Non-Coding RNAs - Function, Mechanisms, and Applications: Function, Mechanisms, and Applications"

LncRNAs contribute to cancer progression by regulating gene expression epigenetically and post-transcriptionally. They influence tumorigenesis through interactions with chromatin modifiers, act as competitive endogenous RNAs to modulate microRNA activity and regulate processes such as epithelial-mesenchymal transition (EMT) that facilitate metastasis. LncRNAs affect cancer cell proliferation, apoptosis, migration, metabolism, and drug resistance, making them crucial players in tumor development and potential targets for diagnosis and therapy. The book covers the latest reports about lncRNAs.

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