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portada Mitochondrial DNA: Methods and Protocols
Type
Physical Book
Publisher
Author
Year
2015
Language
English
Pages
234
Format
Hardcover
Dimensions
26.3x17.9x2 cm
Weight
0.78 kg.
ISBN13
9781493930395
Edition No.
0003
Categories

Mitochondrial DNA: Methods and Protocols

Mckenzie, Matthew (Author) · Humana · Hardcover

Mitochondrial DNA: Methods and Protocols - McKenzie, Matthew

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Synopsis "Mitochondrial DNA: Methods and Protocols"

This third edition is comprised of well-established protocols that are considered the gold standard in the field as well as new methodologies for mitochondrial DNA analysis. of Mitochondrial DNA: Methods and Protocols describes protocols for detecting mutations in mitochondrial DNA, techniques to assess mitochondrial DNA damage, visualization of mitochondrial DNA in situ, detection of mitochondrial DNA nucleoids within the mitochondria, methods for analyzing mitochondrial DNA replication, mitochondrial DNA-encoded protein translation and mitochondrial DNA copy number, the latest technologies for modifying the mitochondrial genome and methods for the purification of proteins involved in the replication and transcription of mitochondrial DNA. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Mitochondrial DNA: Methods and Protocols, Third Edition will be useful not only for mitochondrial researchers but also for scientists studying human diseases where mitochondrial DNA variation has been recognized as an important pathogenic factor, including cancer and neurodegeneration.

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