Name: Molecular Genetics of Inflammatory Bowel Disease
Price: 178.85 EUR
Availability: InStock
Author: D'Amato, Mauro ; Rioux, John D.
ISBN: 9781493942565

portada Molecular Genetics of Inflammatory Bowel Disease

Molecular Genetics of Inflammatory Bowel Disease

Type

Physical Book

Publisher

Springer

Author

D'Amato, Mauro ; Rioux, John D.

Language

English

Pages

343

Format

Paperback

Dimensions

23.4 x 15.6 x 1.9 cm

Weight

0.50 kg.

ISBN13

9781493942565

Synopsis "Molecular Genetics of Inflammatory Bowel Disease"

Research in Crohn's disease (CD) and ulcerative colitis (UC), together known as the inflammatory bowel diseases (IBD), has truly seen a revolution in the last 5-10 years. This book examines how these genetic discoveries have led to the identification of biological functions not previously associated with IBD pathophysiology (e.g. autophagy), how multiple genetic risk factors for IBD converge on given biological functions and that together the identified variants in these genes have predisposing and protective roles (e.g. the multiple variants in the receptor for the IL23 cytokine and its signaling cascade), and how having such a large number of known genetic risk factors has changed our understanding not only about the genetic and molecular overlap between CD and UC, but also between these diseases and other chronic inflammatory diseases (e.g. psoriasis, multiple sclerosis, type 1 diabetes and many others).

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Molecular Genetics of Inflammatory Bowel Disease - D'Amato, Mauro ; Rioux, John D.

Synopsis "Molecular Genetics of Inflammatory Bowel Disease"

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