Name: Myelogenous Leukemia: JAK2V617F Mutation and other Serum level of alkaline phosphatase and Lactate Dehydrogenase
Price: 48.53 EUR
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Author: Al-Jumaily, Essam ; Al-Husseiny, Istabraq Akram Beram
ISBN: 9786200533159

portada Myelogenous Leukemia: JAK2V617F Mutation and other Serum level of alkaline phosphatase and Lactate Dehydrogenase

Myelogenous Leukemia: JAK2V617F Mutation and other Serum level of alkaline phosphatase and Lactate Dehydrogenase

Type

Physical Book

Author

Essam Al-Jumaily

Istabraq Akram Beram Al-Husseiny

Publisher

LAP Lambert Academic Publishing

Language

English

Pages

116

Format

Paperback

Dimensions

22.9 x 15.2 x 0.7 cm

Weight

0.18 kg.

ISBN13

9786200533159

Synopsis "Myelogenous Leukemia: JAK2V617F Mutation and other Serum level of alkaline phosphatase and Lactate Dehydrogenase"

Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm arises from a single genetic translocation in a pluripotential hematopoietic stem cell (HSC). This genetic aberration results in a clonal over-production of the myeloid cell line with a preponderance of immature cells in the neutrophilic line. A hallmark of CML is an abnormal chromosome known as the Philadelphia Chromosome, a genetic or DNA related abnormality that initiates a series of events leading to the development of what is called a Bcr-Abl translocation. This translocation results in an abnormality of an enzyme known as tyrosine kinase causing granulocytes to grow and reproduce rapidly. There is no obvious reason associated with such Philadelphia Chromosome, but the disease is seen predominantly in those aged 46 to 53 years, and is slightly more common in males than in females. Exposure to ionizing radiation and prolonged used of chemotherapy have also been committed as a risk factor for the disease.

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Myelogenous Leukemia: JAK2V617F Mutation and other Serum level of alkaline phosphatase and Lactate Dehydrogenase - Al-Jumaily, Essam ; Al-Husseiny, Istabraq Akram Beram

Synopsis "Myelogenous Leukemia: JAK2V617F Mutation and other Serum level of alkaline phosphatase and Lactate Dehydrogenase"

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