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portada Paediatric Formulation: Design and Development
Type
Physical Book
Publisher
Author
Language
English
Pages
206
Format
Hardcover
Dimensions
24.4x17x1.8 cm
Weight
0.64 kg.
ISBN13
9783036507408
Categories

Paediatric Formulation: Design and Development

Denora, Nunzio ; Lopalco, Antonio (Author) · Mdpi AG · Hardcover

Paediatric Formulation: Design and Development - Denora, Nunzio ; Lopalco, Antonio

New Book Imported to Netherlands
Delivery: 07 Sep - 09 Sep Shipping: 4 to 5 business days.
€ 57,83
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Synopsis "Paediatric Formulation: Design and Development"

The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients.

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