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portada Pharmaco-Imaging in Drug and Biologics Development: Fundamentals and Applications
Type
Physical Book
Publisher
Author
Language
English
Pages
401
Format
Paperback
ISBN13
9781493951741
Categories

Pharmaco-Imaging in Drug and Biologics Development: Fundamentals and Applications

Moyer, Brian R. ; Cheruvu, Narayan P. S. ; Hu, Tom C. -C (Author) · Springer · Paperback

Pharmaco-Imaging in Drug and Biologics Development: Fundamentals and Applications - Moyer, Brian R. ; Cheruvu, Narayan P. S. ; Hu, Tom C. -C

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Synopsis "Pharmaco-Imaging in Drug and Biologics Development: Fundamentals and Applications"

The volume aim to be a comprehensive overview of the drug and biologic development process that is often called "the valley of death" (pre-IND through approval) where high costs of studies and high rates of product failure are part of the drug development landscape. Imaging tools can serve in this period by adding high value data, the images and the kinetic information they can provide, and cost-effective development alternative tools which potentially improve pivotal study designs. Imaging may identify safety issues early such as unwanted organ or tissue distributions, and then can serve advanced development with added certainty of a drug or biologic's success to senior corporate management and investors. There are numerous textbooks, reference texts and treatises on medical imaging technologies, teaching tools on medical cases and physics books on the science of detector and computer interface systems. Rarely, in each of these are examples of medical imaging protocols and animal models of disease i.e. a text on methodology in drug development is currently unavailable.

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