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portada Polyploidization and Cancer
Type
Physical Book
Publisher
Author
Language
English
Pages
151
Format
Paperback
Dimensions
25.4x17.8x0.9 cm
Weight
0.30 kg.
ISBN13
9781493951437
Categories

Polyploidization and Cancer

Poon, Randy Y. C. (Author) · Springer · Paperback

Polyploidization and Cancer - Poon, Randy Y. C.

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Synopsis "Polyploidization and Cancer"

Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overview subjects relating to polyploidization and cancer.

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