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portada UHRF1
Type
Physical Book
Language
English
Format
Paperback
ISBN13
9786131333620

UHRF1

New Book Imported to Netherlands
Delivery: 02 Oct - 06 Oct Shipping: 13 to 14 business days.
€ 162,73
Import costs and 9% BTW included in the price ✅
€ 162,73

Synopsis "UHRF1"

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Ubiquitin-like, containing PHD and RING finger domains, 1, also known as UHRF1, is a protein which in humans is encoded by the UHRF1 gene. This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase II alpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.

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