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portada diverse effects of hypoxia on tumor progression
Type
Physical Book
Illustrated by
Publisher
Year
2012
Language
English
Pages
146
Format
Paperback
Dimensions
22.9 x 15.5 x 1.3 cm
Weight
0.23 kg.
ISBN
3642264840
ISBN13
9783642264849

diverse effects of hypoxia on tumor progression

M. Celeste Simon (Illustrated by) · Springer · Paperback

diverse effects of hypoxia on tumor progression - Simon, M. Celeste

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Synopsis "diverse effects of hypoxia on tumor progression"

Hypoxia, defined as reduced oxygen tension, is a common physiological phenomenon in both normal embryonic development and malignancy progression. Although severe hypoxia is generally toxic for both normal tissue and tumors, neoplastic cells gradually adapt to prolonged hypoxia though additional genetic and genomic changes with a net result that hypoxia promotes tumor progression and therapeutic resistance. Hypoxia promotes cancer progression by regulating various aspects of cancer biology, including radiotherapy resistance, metabolism, angiogenesis and invasion/migration.

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