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portada Polycomb Group Proteins
Type
Physical Book
Publisher
Author
Language
English
Pages
372
Format
Hardcover
ISBN13
9780128097373
Edition No.
1

Polycomb Group Proteins

Vincenzo Pirrotta (Author) · Academic Press · Hardcover

Polycomb Group Proteins - Vincenzo Pirrotta

New Book Imported to Netherlands
Delivery: 22 Sep - 25 Sep Shipping: 10 to 12 business days.
€ 106,47
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Synopsis "Polycomb Group Proteins"

Polycomb Group Proteins is a comprehensive volume detailing the mechanisms that are key to the management of genome function in many different contexts, from embryonic stem cells to terminal differentiation. The book discusses the regulation of cell lineages, cell proliferation, apoptosis, X chromosome inactivation, and most major genome programming choices. In the last few years, the biochemical understanding of PRC1-type complexes has greatly expanded in terms of the number of components involved and the intricacies of their interactions. The functionalities of these various complexes and their components are not all well understood, but recent work has shown an important division of labor and roles in the recruitment of stable binding in the ability to lay the groundwork of histone modifications and in the epigenetic maintenance of repressed states. In an effort to provide clarity in this topical research area, the book provides a cluster of chapters that deal with variant PRC1 complexes, their taxonomy, their components, their interactions, and what is known of their functions.

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