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portada Therapeutic Interventions in the Complement System
Type
Physical Book
Publisher
Author
Language
English
Pages
260
Format
Paperback
Dimensions
22.9 x 15.2 x 1.4 cm
Weight
0.37 kg.
ISBN13
9781468496123
Categories

Therapeutic Interventions in the Complement System

Lambris, John D. ; Holers, V. Michael (Author) · Humana · Paperback

Therapeutic Interventions in the Complement System - Lambris, John D. ; Holers, V. Michael

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Synopsis "Therapeutic Interventions in the Complement System"

A team of expert investigators and clinical researchers comprehensively review complement's basic biology, its role in disease, methods to measure its activity, and strategies for its inhibition in patients. Each chapter focuses on a specific area of basic and applied complement biology, spelling out the activation pathways and complement receptors. Informative animal models are discussed in detail, including the relative values of each model and the important interspecies differences that can distort the interpretation of preclinical studies. The emphasis throughout is on the pros and cons of the therapeutic use of recombinant complement inhibitors in specific diseases. Cutting-edge and innovative, Therapeutic Interventions in the Complement System highlights for today's researcher and biotechnologist effective strategies of drug discovery and development that are producing valuable new complement inhibitors for the treatment of a wide variety of clinically important diseases.

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